KDevelop has an almost boundless list of keyboard shortcuts (some of them are listed in the “Useful keyboard shortcuts sections” of several chapters in this manual) that can be changed to your taste through the menu Settings → Configure Shortcuts. At the top of the dialog you can enter a searchword and it only shows those commands that match; you can then edit which key combination is bound to this command.

Two that have been found to be very useful to change are to set Align to the Tab key (many people don't usually enter tabs by hand and rather prefer if the editor chooses the layout of code; with the changed shortcut, hitting Tab makes KDevelop indent/outdent/align the code). The second one is putting Toggle Breakpoint on Ctrl+B since this is quite a frequent operation.